Skip to content

Cannabiz Depot – A Leader in Cannabis Throughout the Nation

Cannabis You Can Trust

Our premium Cannabis products are designed to relieve many symptoms, whether it’s for you or your pets.

Cannabiz Depot – Your Go-To Shop For All Things Cannabis And THC

Our Vision

The Cannabiz Depot mission is to be a customer-driven, community-focused, industry leader in the cannabis retail market. We take pride in the quality of products that we offer and prices we sell them at. We feel that high-quality THC products should be affordable to everyone. We are passionate about cannabis!



With multiple locations and an online store, our products are accessible though a number of ways. When visiting one of our locations, a Cannabis Consultant will greet you as you enter our modern, clean dispensary. They will ask questions to learn more about your specific situation and work to earn your trust. We aim to build long-lasting relationships with our guests by providing honest and credible information about the cannabis industry and the products we offer so you can make educated buying decisions based on your needs. 

Our staff and owners are dedicated to you! Whether you are looking to learn more about Cannabis and THC or peruse our large selection of products, we have you covered when it comes to cannabis!

All of the cannabis products that we sell at Cannabiz Depot have been 3rd party lab tested and contain less than 0.3% THC.

Great Deals For Any CannaBudget

Each Cannabiz Depot location has their own special offers and daily deals. Like product discounts, hazy hour, and more.

Your One-Stop Shop for Premium Cannabis Products

Cannabiz Depot offers a vast selection of quality Cannabis products. This includes clothing & accessories, bath & beauty products, pet care products, body care products, and more.   

Bath & Beauty


Food & Beverages


Clothing & Accessories

Stop By Our Stores & Say “High”!

Cannabiz Depot welcomes guests across multiple locations, offering a unique shopping experience for those interested in exploring quality cannabis products. From the inviting atmosphere of our original retail store in historic downtown La Crosse, Wisconsin, to the friendly community settings of Holmen, Wisconsin, Houma, Louisiana, and Osage Beach, Missouri, each Cannabiz Depot store is designed to make visitors feel at home.

Our stores serve as local hubs where arts, entertainment, and the spirit of community converge. Whether you’re looking for a specific product or just curious about what we have to offer, our knowledgeable staff are eager to provide a personalized shopping experience. At Cannabiz Depot, we’re more than a retail space—we’re a destination for those seeking both quality and education in their cannabis journey.

We take pride in our roots and the diverse communities we serve. Each location reflects the unique character of its surroundings while sharing the same commitment to quality and service. Drop by to discover our wide range of products and let us share with you the Cannabiz Depot experience that goes beyond expectations.

Follow Us On Instagram 



We love our customers, especially loyal ones. To show our appreciation, we created a loyalty program with the following CBDeece perks:

  • $5 off chip with a purchase of $75+
  • Spin the CBDeal of Fortune and have a chance to win a discount or free product with a purchase of $75+
  • $5 credit after you earn 100pts (1pt = $1 spent)
  • Birthday gifts – 1 free pre-roll the day of your birthday, and 20% off 1 purchase during your birthday week
  • Monthly store e-mail
  • Social media giveaways
  • Daily deals
  • Opportunities to win free swag on a daily basis

Plus, all customers who purchase a $25 gift card will receive a $5 chip.

Sign-Up For Our Monthly Newsletter / Loyalty Program

Join today and receive monthly product updates, coupons, special offers, and more!

Franchises Available Nationwide

Cannabiz Depot is a locally-owned, cannabis retail outlet that opened its first location at 200 4th St. S La Crosse, WI 54601. Everything in our stores is related to the cannabis plant. This includes our food & beverages, clothing & accessories, bath & beauty line, health & wellness products, pet products, and much more.

Joining Cannabiz Depot as a franchisee provides access to premium cannabis products and a one-stop-shop advantage in a growing market. Benefit from an established brand, a suite of marketing tools, comprehensive training, and strong potential earnings with strategic support for a successful launch and sustained growth.


Community Focused

We are always looking for ways to give back to the community. Which is why we partnered up with Beer by Bike Brigade in La Crosse, Wisconsin to help pay off school lunch debt by donating 10% of our sales from CBD food and drink purchases. Check out the story here.

Our plan is to continue to give back to our communities in a variety of ways including causes like animal rescue, mental health, addiction, and poverty.